As I lifted the lid from my baking dish, a wave of garlic and butter enveloped me like a warm hug, instantly transporting me to a cozy Italian kitchen. Today, I’m thrilled to share my recipe for Garlic Butter Shrimp Scampi Lasagna, a delightful fusion of creamy comfort and savory seafood. This dish is not just a comforting treat; it’s also surprisingly simple to prepare, making it a perfect choice for both special occasions and weeknight dinners. Picture tender shrimp nestled between layers of rich cheese and perfectly baked noodles, all united by that irresistible garlic butter sauce. Whether you’re hosting friends or simply craving a satisfying meal, this lasagna is ready to impress. Ready to dive into something delicious? Let’s cook!
Why Is This Lasagna So Irresistible?
Layers of Flavor: Each bite of this Garlic Butter Shrimp Scampi Lasagna is a delightful explosion of creamy cheese and succulent shrimp, perfectly melding together in a savory garlic sauce.
Ease of Preparation: With straightforward steps, this dish is suitable for everyone, from novice cooks to seasoned chefs seeking a quick weeknight meal or a crowd-pleasing option for special gatherings.
Versatile Ingredients: Feel free to mix it up! You can substitute shrimp for crab or lobster, or even add some fresh spinach for a nutritious twist.
Comfort Food Redefined: This recipe elevates your standard lasagna to a whole new level. It’s a cozy dish that is bold enough to create lasting memories.
Perfect Pairing: Serve it alongside a crisp green salad or some garlic bread for the ultimate meal experience, reminiscent of your favorite Italian restaurant. Don’t forget to check out our other popular recipes, like Garlic Shrimp Pasta or Butternut Squash Lasagna, for more delicious ideas!
Garlic Butter Shrimp Scampi Lasagna Ingredients
• Dive into the richness of flavors with these essential ingredients that make your Garlic Butter Shrimp Scampi Lasagna unforgettable!
For the Sauce
- Butter – Adds richness and flavor to the sauce. Use olive oil for a lighter option.
- Garlic – Provides depth and aromatic flavor. Fresh minced garlic is preferred.
- Heavy Cream – Creates a rich and creamy sauce. Substitute with half-and-half for a lighter texture.
- Chicken Broth – Provides a balanced, savory base. Use vegetable broth for a pescatarian option.
- Lemon Zest & Juice – Brightens the dish and enhances flavors. Fresh lemon is ideal.
- Salt & Black Pepper – Essential seasonings for flavor enhancement. Adjust to taste.
- Crushed Red Pepper Flakes – Adds heat and spice. Adjust quantity based on taste preference.
For the Lasagna
- Large Shrimp – The main protein; offers sweet and succulent bites. Substitute with scallops or crab for variation.
- Lasagna Noodles – Forms the structure of the dish. Gluten-free noodles can be used for dietary restrictions.
For the Cheese Layers
- Ricotta Cheese – Contributes creaminess and acts as a filling layer. Substitute with cottage cheese if desired.
- Shredded Mozzarella Cheese – Melts perfectly and adds stretch. Use a mix of mozzarella and provolone for a flavor twist.
- Grated Parmesan Cheese – Enhances the umami flavors and adds a nutty aroma.
For Garnish
- Chopped Fresh Parsley – Provides freshness and color. Substitute with basil or chives for variation.
- Olive Oil – Used to drizzle the pan, preventing sticking; optional based on preference.
Step‑by‑Step Instructions for Garlic Butter Shrimp Scampi Lasagna
Step 1: Sauté the Garlic
Begin by melting 2 tablespoons of butter in a large skillet over medium heat. Once it’s melted and bubbling, add 3 cloves of minced garlic and sauté for about 1 minute until fragrant—be careful not to let it burn, as this can turn the flavor bitter.
Step 2: Cook the Shrimp
Add 1 pound of peeled and deveined large shrimp to the skillet. Cook for 2-3 minutes until the shrimp are pink and opaque. Once done, remove the shrimp from the skillet and set them aside on a plate, leaving the flavorful remnants in the pan for the sauce.
Step 3: Prepare the Sauce
In the same skillet, pour in 1 cup of heavy cream and 1 cup of chicken broth. Stir in the zest and juice of 1 lemon, followed by a pinch of salt, black pepper, and ½ teaspoon of crushed red pepper flakes. Bring the mixture to a gentle simmer over medium heat for about 5 minutes until slightly thickened, stirring occasionally.
Step 4: Incorporate the Cheeses
Lower the heat and stir in 1 cup of ricotta cheese, followed by 1 cup of shredded mozzarella and ½ cup of grated Parmesan cheese. Keep stirring until the cheeses melt and blend completely, creating a creamy sauce. This rich mixture forms the base for your Garlic Butter Shrimp Scampi Lasagna.
Step 5: Add the Shrimp Back
Return the cooked shrimp to the skillet, and gently fold them into the creamy sauce. Allow it to heat for another minute on low heat, ensuring the shrimp are properly coated and warmed through. This flavor-packed mixture brings your lasagna to life.
Step 6: Preheat the Oven
While the shrimp mixture is heating, preheat your oven to 375°F (190°C). This temperature ensures a perfectly baked lasagna with a bubbly, golden crust.
Step 7: Layer the Lasagna
In a greased baking dish, start layering your lasagna. Place a layer of lasagna noodles at the bottom, followed by a generous layer of the shrimp and sauce mixture. Repeat the layers, finishing with noodles and a top layer of cheese. This assembly creates those delightful flavors in each bite of your Garlic Butter Shrimp Scampi Lasagna.
Step 8: Bake the Lasagna
Cover the baking dish with aluminum foil to prevent excessive browning and bake in the preheated oven for 25 minutes. After this time, carefully remove the foil and bake for an additional 10 minutes until the cheese on top is bubbly and golden brown, creating an irresistible aroma.
Step 9: Let It Cool
Remove the lasagna from the oven and let it cool for about 10 minutes. This resting time helps the layers set, making it easier to slice. Your Garlic Butter Shrimp Scampi Lasagna is almost ready to serve!
Step 10: Garnish and Serve
Sprinkle freshly chopped parsley over the top for a touch of color and freshness just before serving. This simple garnish enhances not only the appearance but also the flavor of your luxurious lasagna, inviting everyone to dig in!
How to Store and Freeze Garlic Butter Shrimp Scampi Lasagna
Fridge: Store any leftovers in an airtight container for up to 3 days. Make sure to let the lasagna cool before sealing to maintain its perfect texture.
Freezer: For longer storage, wrap each portion tightly in plastic wrap and then in aluminum foil to prevent freezer burn. It can be frozen for up to 3 months.
Reheating: Thaw in the fridge overnight, then reheat in a covered dish at 350°F (175°C) for about 25-30 minutes or until heated through. Add a splash of cream to restore moisture if needed.
Serving Note: The flavors of the Garlic Butter Shrimp Scampi Lasagna actually improve after a day, making leftovers a delicious treat!
Garlic Butter Shrimp Scampi Lasagna Variations
Feel free to embrace your culinary creativity and customize this dish to match your taste buds and dietary needs!
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Seafood Swap: Replace shrimp with crab meat, lobster, or a mix of seafood for a luxurious twist.
The delicate flavors of crab can elevate your lasagna, infusing it with that beachy zest everyone loves. -
Veggie Boost: Add layers of fresh spinach or sun-dried tomatoes for a nutritious enhancement.
The spinach adds a pop of color and health, while the tomatoes contribute a tangy sweetness that pairs beautifully. -
Dairy-Free Delight: Use a dairy-free cream and cheese alternative for those lactose intolerant.
There are excellent plant-based cheeses that melt well, ensuring you won’t miss out on that creamy texture. -
Gluten-Free Option: Swap regular lasagna noodles for gluten-free alternatives to accommodate dietary restrictions.
This way, everyone can enjoy a slice of this creamy seafood goodness without any worries. -
Spicy Kick: Incorporate jalapeños or sriracha for an exciting heat level that ignites your taste buds.
These additions bring a lovely contrast to the sweetness of the shrimp, making each bite an adventure. -
Herb Infusion: Experiment with fresh herbs like basil or chives instead of parsley for a distinct taste.
Fresh herbs can really uplift the dish, bringing a garden-fresh aroma as you savor each forkful. -
Creamy Elegance: Mix in a touch of mascarpone or cream cheese for an extra-rich flavor profile.
This luscious addition will wrap each noodle with velvety creaminess, bringing your lasagna to new heights.
While you’re at it, you might also enjoy serving your lasagna alongside a refreshing green salad or some garlic bread. And if you’re looking for more ideas, don’t miss out on our delicious Cheese Shrimp Penne or comforting Chicken Alfredo Garlic recipes!
Expert Tips for Garlic Butter Shrimp Scampi Lasagna
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Garlic Quality Matters: Use fresh minced garlic for the best flavor. Avoid pre-minced garlic, which can lack the depth and vibrancy needed for this dish.
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Shrimp Preparation: Ensure shrimp are properly peeled and deveined before cooking to avoid any gritty textures. Quick cooking ensures they remain juicy and tender.
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Layering Techniques: Alternate layers of noodles and sauce to prevent noodles from sticking together. Make sure some sauce is always on top to keep the lasagna moist.
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Resting Period: Allow the Garlic Butter Shrimp Scampi Lasagna to rest for about 10 minutes after baking. This helps the layers set for cleaner slices.
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Covering While Baking: Initially cover the dish with foil to steam the lasagna, then uncover for the last few minutes to achieve that bubbly golden crust.
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Experiment with Cheese: Feel free to mix cheeses like provolone or use low-fat options to customize the richness of your Garlic Butter Shrimp Scampi Lasagna.
Make Ahead Options
These Garlic Butter Shrimp Scampi Lasagna layers are perfect for meal prep enthusiasts looking to save time on busy weeknights! You can prepare the entire lasagna up to 24 hours in advance by assembling it in your baking dish, then covering it tightly with foil and refrigerating. Just keep in mind to let it sit at room temperature for about 30 minutes before baking to ensure it cooks evenly. If you’re prepping on the weekend, you can store cooked shrimp in the fridge for up to 3 days, and quickly fold them into the creamy sauce before layering. When ready to bake, simply uncover and pop it in the preheated oven, and you’ll enjoy delicious, home-cooked comfort with minimal effort!
What to Serve with Garlic Butter Shrimp Scampi Lasagna
Elevate your meal experience with perfect pairings that enhance the delightful flavors of this creamy seafood hug in a dish.
- Garlic Bread: Satisfyingly crunchy and warm, it’s perfect for soaking up all that rich garlic butter sauce.
- Crisp Green Salad: A refreshing blend of greens and vinaigrette adds a vibrant crunch, balancing the creamy lasagna beautifully.
- Roasted Asparagus: Tender, slightly caramelized, and drizzled with lemon, it complements the seafood wonderfully and adds an elegant touch.
- Herbed Couscous: Light and fluffy with a hint of lemon, it brings a contrasting texture and lightness to the meal, making each bite feel less heavy.
- White Wine Spritzer: A refreshing drink that cuts through the richness of the lasagna; the fruity notes make every sip delightful.
- Lemon Sorbet: A palate cleanser that purifies the taste buds, leaving a zesty finish after every delicious bite.
- Bruschetta: Topped with fresh tomatoes and basil, it can awaken your taste buds, preparing them for the satisfying layers of the lasagna.
- Zucchini Noodles: For a lighter twist, spiralize zucchini to serve as a side; these veggie noodles add vibrant color and nutrition to your plate.
- Classic Caesar Salad: The creamy dressing and crunchy croutons echo the lasagna’s flavors while introducing a classic pairing to the table.
Garlic Butter Shrimp Scampi Lasagna Recipe FAQs
How do I choose the best shrimp for this recipe?
Absolutely! When selecting shrimp, look for large, firm, and brightly colored ones that smell fresh and not overly fishy. I recommend avoiding any shrimp with dark spots or a strong ammonia scent, as these are signs of spoilage. If you can, buy wild-caught shrimp for better flavor.
How should I store leftovers of Garlic Butter Shrimp Scampi Lasagna?
For sure! Store any leftovers in an airtight container in the refrigerator for up to 3 days. Make sure the lasagna is completely cooled before sealing to preserve its creamy texture. I often use glass containers for easy reheating.
Can I freeze Garlic Butter Shrimp Scampi Lasagna?
Definitely! To freeze, wrap the lasagna tightly in plastic wrap and then in aluminum foil to prevent freezer burn. It can be frozen for up to 3 months. When you’re ready to enjoy it again, thaw it overnight in the fridge, and reheat at 350°F (175°C) for about 25-30 minutes, adding a splash of cream to keep it moist.
What if my lasagna is too watery?
Very good question! If your lasagna turns out watery, it may be due to excess moisture from the shrimp or sauce. To troubleshoot, you can let the dish rest for a while after baking, as this allows some liquid to absorb. Alternatively, you can reduce the sauce ingredients slightly before layering to ensure a thicker consistency.
Is this recipe suitable for people with seafood allergies?
Great consideration! This Garlic Butter Shrimp Scampi Lasagna is not suitable for those with seafood allergies. However, you can modify the recipe by using chicken or a mix of vegetables such as spinach and mushrooms for a flavorful vegetarian alternative. Just ensure to adjust the cooking time accordingly.
What can I substitute for ricotta cheese if necessary?
Perfectly fine! If you’re looking to substitute ricotta cheese, cottage cheese is a great option and offers a similar texture, though with a slightly different flavor. You can even blend the cottage cheese beforehand to make it smoother for layering.

Garlic Butter Shrimp Scampi Lasagna: A Creamy Seafood Dream
Ingredients
Equipment
Method
- Melt 2 tablespoons of butter in a large skillet over medium heat. Sauté 3 cloves of minced garlic for about 1 minute until fragrant.
- Add 1 pound of large shrimp to the skillet. Cook for 2-3 minutes until pink and opaque, then remove them and set aside.
- In the skillet, combine 1 cup of heavy cream and 1 cup of chicken broth. Stir in lemon zest and juice, salt, pepper, and red pepper flakes. Simmer for about 5 minutes until thickened.
- Stir in 1 cup of ricotta cheese, 1 cup of shredded mozzarella, and ½ cup of grated Parmesan until melted and blended.
- Return shrimp to the skillet and fold into the creamy sauce, heating for another minute.
- Preheat oven to 375°F (190°C).
- Layer lasagna in a greased baking dish, starting with noodles, followed by shrimp mixture, and repeat, finishing with noodles and cheese on top.
- Cover with aluminum foil and bake for 25 minutes. Remove foil and bake for another 10 minutes until bubbly and golden.
- Let cool for about 10 minutes before serving.
- Garnish with chopped parsley before serving.